Grand Rounds vol. 3, no. 2 has been posted at RDoctor Medical.
Abel explains, in the first part of a promised series. This is a topic I’ve been meaning to write about for a long time but somehow never got around to it. Abel explains nicely the barriers to drug absorption, distribution, and activity and why it’s very bad science for alties to try to extrapolate from studies of cells cultured in dishes to humans. In fact, toxicity to cultured cancer cells correlates only weakly with efficacy in an actual human, thanks to many of the factors Abel explains. I would also point out that I’m involved as a coinvestigator in the …
I knew there was a reason that I don’t often blog about politics, and yesterday reminded me of it. Maybe I should have just launched another enthusiastic debunking of the distortions and outright false information put out by antivaccination advocates like Dawn Winkler. Instead, I thought it might be educational to return to a topic that I haven’t revisited in a while, so-called HIV/AIDS “dissidents.” These cranks resemble antivaxers in their fast-and-loose approach to and cherry-picking of the data, along with some outright misrepresentations of studies. They’re at it again. This time around, they’re misrepresenting a paper:
The latest History Carnival has been posted at Old is the New New. Enjoy!