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Bad science Bioethics Clinical trials Medicine Politics

The cult of hydroxychloroquine versus dangerous arrhythmias

A new study of #Hydroxychloroquine and #Chloroquine to treat #COVID19 was published this morning in The Lancet. The results? More deaths and arrhythmias in treated patients. [NOTE ADDENDUM: This study has been retracted. Here’s a link to my followup post.]

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Bad science Bioethics Clinical trials Medicine Popular culture Skepticism/critical thinking

Dr. Didier Raoult: Bad science on COVID-19 and bullying critics

Didier Raoult is the French “brave maverick doctor” who’s been promoting hydroxychloroquine and azithromycin to treat COVID-19. Like all true cranks, he’s now lashing out at critics as the science trends towards the conclusion that his treatment doesn’t work.

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Bad science Bioethics Clinical trials Medicine Politics Popular culture Pseudoscience

Drs. Vladimir Zelenko and Stephen Smith: Abandoning evidence-based medicine to promote unproven drugs for COVID-19

Drs. Vladimir Zelenko and Stephen Smith have been claiming that hydroxychloroquine is a miracle drug based on anecdotes. Their shoddy, poorly reported case series are not evidence of efficacy.

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Autism Bioethics Cancer Clinical trials Complementary and alternative medicine Integrative medicine Medicine Pseudoscience Quackery

dōTERRA Center for Integrative Oncology: St. Elizabeth Healthcare sells out to an MLM company hawking essential oils

St. Elizabeth Healthcare in Cincinnati recently accepted $5 million from dōTERRA, an MLM company selling essential oils based on dubious claims. This is most definitely not a good look.

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Bioethics Clinical trials Medicine

Libella Gene Therapeutics: Charging $1 million to participate in a phase 1 trial of anti-aging gene therapy

Libella Gene Therapeutics, LLC made the news last week for announcing a “pay-to-play” trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it was a “pay-to-play” trial, given that such trials have become all too common, but rather the price of enrollment: $1 million. Worse, the trial is being conducted in Colombia; the therapy doesn’t have the greatest preclinical justification; and it’s a phase 1 trial, which means it is only trial of safety, not efficacy. How can unethical and scientifically dubious trials like this be stopped?