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Bioethics Clinical trials History Holocaust Medicine World War II

Revisiting the issue of ethics in human experimentation

Progress in science-based medicine depends upon human experimentation. Scientists can do the most fantastic translational research in the world, starting with elegant hypotheses, tested through in vitro and biochemical experiments, after which they are tested in animals. They can understand disease mechanisms to the individual amino acid level in a protein or nucleotide in a […]

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Bioethics Complementary and alternative medicine Medicine Quackery

Another teen endangered by “alternative medicine,” part 2

Judge Orders Surgery For Teen Wrestler: MyFoxPHILLY.com I have to be honest here. I don’t know for sure what I think of the latest developments in the Mazeratti Mitchell case. As you may recall from a couple of days ago, Mazeratti Mitchell is a 16 year old wrestler in Philadelphia who suffered a spinal cord […]

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Autism Bioethics Complementary and alternative medicine Homeopathy Medicine Pseudoscience Skepticism/critical thinking

Luc Montagnier: The Nobel disease strikes again

They call it the Nobel disease. Linus Pauling is the prototypical example. A brilliant chemist who won two Nobel Prizes, one for chemistry and the Nobel Peace Prize, in his later years Pauling became convinced that high dose vitamin C was a highly effective treatment for cancer and the common cold and, expanding upon that, […]

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Antivaccine nonsense Autism Bioethics Biology Evolution Intelligent design/creationism Medicine Science Skepticism/critical thinking

The strange science and ethics of the anti-vaccine movement

One of the great things about having declared Vaccine Awareness Week is that it gives me a convenient excuse to revisit topics and blog posts that I had meant to address but that somehow didn’t make the cut the first time around. This is the sort of thing that happens fairly frequently in blogging, where […]

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Bioethics Clinical trials Complementary and alternative medicine Medicine Politics Quackery Science

The Guatemala syphilis experiment, human subjects research abuses, and CAM

If there’s one thing that burns me about so-called “complementary and alternative medicine” (CAM) clinical trials, it’s how unethical many of them are. This is particularly true for trials that test modalities that, on the basic science grounds alone, can be dismissed as so highly implausible and with such a low prior probability of success […]