Category: Biology

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Antivaccine nonsense Autism Biology Medicine Pseudoscience Quackery Science Skepticism/critical thinking

Torturing more mice in the name of antivaccine pseudoscience: PubPeer versus antivaxers

Mouse
"Why, oh, why do I have to die in the cause of such crappy science?"

Last week, I wrote about a truly execrable bit of science by Christopher Shaw and Lucija Tomljenovic purporting to show that aluminum adjuvants cause brain inflammation, which causes autism. Since then, I’ve learned that, not only is it bad science, but that there are red flags about several of the figures to raise the specter of fraud. This might not be just bad science. It might be fraudulent science. The only way to resolve this would be for the authors to release the original full resolution images of their blots.

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Antivaccine nonsense Autism Bioethics Biology Pseudoscience Skepticism/critical thinking

Torturing more mice in the name of antivaccine pseudoscience, 2017 aluminum edition

Mouse
"Why, oh, why do I have to die in the cause of such crappy science?"

Over the last couple of days I noted a disturbance in the antivaccine force, another study claimed to be slam dunk evidence that aluminum adjuvants in vaccines cause autism. It’s not. Also, a word to antivaxers challenging Orac to look at this study: Be very careful what you wish for…

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Biology Cancer Computers and social media Medicine

IBM Watson: Not living up to hype as a tool to fight cancer?

IBM Watson: Great at Jeopardy!, but it remains to be seen how well Watson handles cancer.

Five years ago, IBM announced that its supercomputer Watson would revolutionize cancer treatment by using its artificial intelligence to digest and distill the thousands of oncology studies published every year plus patient-level data and expert recommendations into treatment recommendation. Last week, a report published by STAT News shows that, years later, IBM’s hubris and hype have crashed into reality.

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Bioethics Biology Clinical trials Medicine Politics

Shame! Another front in the libertarian war on the FDA: Rational Vaccines’ unethical offshore herpes vaccine clinical trial

The shame this unethical clinical trial deserves cannot be overemphasized.

I’ve discussed so-called “right-to-try” laws, which promise to speed experimental drugs to terminally ill patients, but which in reality are about weakening and bypassing the FDA. Now über-Libertarian Peter Thiel is trying a new tactic to bypass the FDA by organizing an offshore clinical trial of a new herpes vaccine based on dubious science and not overseen by an IRB to protect patients. Both right-to-try and this trial are different fronts in the same fundamentalist free market war on FDA regulation.

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Biology Cancer Medicine Skepticism/critical thinking

Does chemotherapy work? Chemotherapy vs. “spreading” cancer.

Illustration of breast cancer cells.

Earlier this month, cancer quacks everywhere were touting a study that suggests that chemotherapy administered before breast cancer treatment can stimulate the spread of cancer, pointing to it as evidence that chemotherapy doesn’t work and even makes cancer worse. In reality, the study was far more nuanced. It didn’t show that chemotherapy doesn’t work (quite the contrary) but does point to ways we can make chemotherapy more effective.