I’ve written many times about how the relationship between the early detection of cancer and decreased mortality from cancer is not nearly as straightforward as the average person—even the average doctor—thinks, the first time being in the very first year of this blog’s existence. Since then, the complexities and overpromising of various screening modalities designed […]
One of the limitations constraining those of us who do human subjects research is that ethical considerations often prevent us from designing our clinical trials in what would be, from a strictly scientific standpoint, in the most methodologically rigorous way. For example, we can’t intentionally infect human beings with known inocula of deadly bacteria in […]
As hard as it is to believe after over ten years of existence and over 5,000 posts on SBM, every so often, something reminds me that I’ve missed paper that cries out for some not-so-Respectful Insolence. So it was a couple of weeks ago, when I saw a familiar name in a news story that […]
Readers of this blog of a certain age and above are likely to remember a U.S. Senator from Wisconsin named William Proxmire. Sen. Proxmire made a name for himself in the late 1970s and throughout much of the 1980s by issuing what he dubbed “The Golden Fleece Award,” which was meant to “honor” public officials […]
Yesterday was a long day, starting in the operating room and finishing at a dinner reception for our visiting speaker today. As a result, when I arrived home, I was sawing the proverbial logs within five or ten minutes of hitting the couch, more or less without realizing it. I was going to just skip […]
