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Clinical trials Medicine Science

Things like this make medical science worthwhile: A drug to treat genetic diseases due to nonsense mutations

There are times when, as a scientist, I look at an idea and its execution and simply stand in awe. It’s particularly satisfying when it’s a relatively simple idea that could conceivably do a lot of good for a lot of patients. Oddly enough, whether it’s because I’ve been out of the loop or because […]

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Clinical trials Complementary and alternative medicine Medicine Skepticism/critical thinking

Your tax dollars at work: Tai Chi as an immune booster?

If you ever want to wonder why I’m sometimes of the mind that the National Center for Complementary and Alternative Medicine should be disbanded and its functions distributed among the other Institutes of the NIH, you just have to consider the sorts of woo-filled studies (like the Gonzalez protocol) funded by NCCAM mixed in among […]

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Bioethics Cancer Clinical trials Medicine

Dichloroacetate and The DCA Site: A low bar for “success”

It’s been a couple of weeks since we last checked in with The DCA Site, that dubious advertising site for BuyDCA.com, where a chemist named Jim Tassano sells to desperate cancer patients non-pharmaceutical grade and non-FDA-approved dichloroacetate, the small molecule chemotherapeutic agent with an interesting and unusual mechanism of action that has shown promise in […]

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Bioethics Cancer Clinical trials Medicine Quackery

Checking in with The DCA Site

It’s been a week since I last wrote about dichloroacetate (DCA), the chemotherapeutic agent that targets tumor cells by an interesting new mechanism based on the Warburg effect, as I’ve described in the past. After a very interesting article in Cancer Cell in January by investigators at the University of Alberta, the blogosphere erupted with […]

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Bioethics Cancer Clinical trials Complementary and alternative medicine Medicine

Dichloroacetate (DCA) and cancer: Magical thinking versus Tumor Biology 101

Late yesterday afternoon, I was lazily checking my referral logs to see who might be linking to Respectful Insolence™, as most bloggers like to do from time to time (and any blogger who claims otherwise is probably feeding you a line), when I noticed a fairly large number of visits coming from one location, namely […]