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Bioethics Cancer Clinical trials Medicine

Dichloroacetate and The DCA Site: A low bar for “success”

It’s been a couple of weeks since we last checked in with The DCA Site, that dubious advertising site for BuyDCA.com, where a chemist named Jim Tassano sells to desperate cancer patients non-pharmaceutical grade and non-FDA-approved dichloroacetate, the small molecule chemotherapeutic agent with an interesting and unusual mechanism of action that has shown promise in […]

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Bioethics Cancer Clinical trials Medicine Quackery

Checking in with The DCA Site

It’s been a week since I last wrote about dichloroacetate (DCA), the chemotherapeutic agent that targets tumor cells by an interesting new mechanism based on the Warburg effect, as I’ve described in the past. After a very interesting article in Cancer Cell in January by investigators at the University of Alberta, the blogosphere erupted with […]

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Bioethics Cancer Clinical trials Complementary and alternative medicine Medicine

Dichloroacetate (DCA) and cancer: Magical thinking versus Tumor Biology 101

Late yesterday afternoon, I was lazily checking my referral logs to see who might be linking to Respectful Insolence™, as most bloggers like to do from time to time (and any blogger who claims otherwise is probably feeding you a line), when I noticed a fairly large number of visits coming from one location, namely […]

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Bioethics Cancer Clinical trials Medicine

More links on dichloroacetate (DCA) and cancer for your edification

Although I’ve been blogging alot about dichloroacetate, the small molecule chemotherapeutic agent that has shown promise against a variety of cancers in preclinical animal tumor models, but I’m not the only one. Fellow ScienceBlogger Abel Pharmboy, whose knowledge of pharmacology surpasses my own, has also been on the case and has produced some articles worth […]

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Clinical trials Complementary and alternative medicine Evolution Medicine Science Skepticism/critical thinking

The “individualization” of medical treatments, revisited with evolution

The longer I maintain this blog, the more I find unexpected (to me, at least) intersections and relationships between various topics that I write about. Of course, a lot of it simply has to do with the fact that one of the overarching themes of this blog is skepticism and critical thinking, which leads one […]