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Clinical trials Complementary and alternative medicine Quackery Science

Straw men everywhere about evidence-based medicine

NOTE: Orac is on vacation recharging his Tarial cells and interacting with ion channel scientists, as a good computer should. In the meantime, he is rerunning oldies but goodies, classics, even. (OK, let’s not get carried away.) Here’s one from all the way back in 2007. Notice how, the more things change, the more they […]

Categories
Cancer Clinical trials Science Skepticism/critical thinking

Precision medicine: Hype over hope?

I am fortunate to have become a physician in a time of great scientific progress. Back when I was in college and medical school, the thought that we would one day be able to sequence the human genome (and now sequence hundreds of cancer genomes), to measure the expression of every gene in the genome […]

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Clinical trials Medicine

Acupuncture bait and switch: Electrified hot flash edition

It’s always disappointing to see a good journal fall for bad medicine, particularly when it’s in your field. For example, the Journal of Clinical Oncology (affectionately referred to by its abbreviation JCO) is the official journal of the American Society of Clinical Oncology (ASCO) and probably the most read clinical journal by those involved in […]

Categories
Cancer Clinical trials Science

How should we treat stage 0 breast cancer?

I’ve written more times than I can remember about the phenomenon of overdiagnosis and the phenomenon that is linked at the hip with it, overtreatment. Overdiagnosis is a problem that arises when large populations of asymptomatic, apparently healthy people are screened for a disease or a condition, the idea being that catching the disease at […]

Categories
Clinical trials Complementary and alternative medicine Medicine Quackery Science

An acupuncture bait and switch on hypertension

Acupuncture is a theatrical placebo, but it’s hard not to grudgingly admire just how—shall we say?—malleable or adaptable a placebo it is. What I mean by this is that, if you believe its practitioners and adherents, acupuncture can treat almost literally any disease or health problem. Any! Pain? Acupuncture. Allergies? Acupuncture. Biliary colic? Acupuncture. Infertility? […]