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Clinical trials Complementary and alternative medicine Medicine Popular culture Science Skepticism/critical thinking

Better late than never: Orac comments on the hijacking of evidence-based medicine

It’s no secret that I’m a fan of John Ioannidis. (If you don’t believe me, just type Ioannidis’ name into the blog search box and see how many posts you find.) Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, […]

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Biology Cancer Clinical trials Medicine Pseudoscience Skepticism/critical thinking

Is there a reproducibility "crisis" in biomedical research?

Most scientists I know get a chuckle out of the Journal of Irreproducible Results (JIR), a humor journal that often parodies scientific papers. Back in the day, we used to chuckle at articles like “Any Eye for an Eye for an Arm and a Leg: Applied Dysfunctional Measurement” and “A Double Blind Efficacy Trial of […]

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Complementary and alternative medicine Medicine Science Skepticism/critical thinking

Science isn’t perfect, but it’s better than the alternative.

It often comes as a surprise to proponents of alternative medicine and critics of big pharma that I’m a big fan of John Ioannidis. Evidence of this can easily be found right here on this very blog just by entering Ioannidis’ name into the search box. Indeed, my first post about an Ioannidis paper is […]

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Bad science Medicine Skepticism/critical thinking

GenoPalate and “personalized” DNA-based diet recommendations: More like astrology than science

GenoPalate is a company that claims to give “personalized” dietary recommendations based on DNA testing. Unfortunately, what is provided by such companies is more akin to astrology than science.

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Antivaccine nonsense Biology Cancer Clinical trials Complementary and alternative medicine Medicine Science Skepticism/critical thinking

John Oliver teaches us how to interpret medical and scientific studies

It’s no secret that I’m a big fan of John Oliver. When my aging body allows me to stay awake late enough on Sunday nights and there’s a new episode on, I’ll almost always be watching. Since starting his own show Last Week Tonight With John Oliver on HBO, Oliver’s become quite the expert at […]