As I write this, I am winging my way home from the 2014 meeting of the American Association for Cancer Research (AACR, Twitter hashtag #AACR14) in San Diego. (OK, I’m revising this to fit the format and, of course, the Insolence of this particular blog. Shockingly, I didn’t have as much time to blog in San Diego as I had thought I would. Go figure.) Basically, the AACR meeting is one of the largest meetings of basic and translational cancer researchers in the world. I try to go every year, and pretty much have succeeded since around 1998 or 1999. …
Search results for: cancer overdiagnosis
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Microsoft vows to “solve cancer” in a decade. Hubris ensues.
If there’s one thing that irritates me more than government agencies making bold proclamations about making progress in cancer but not providing sufficient funding to have even a shot of realizing such ambitions (I’m talking to you, Cancer Moonshot), it’s people in other disciplines that are not cancer biology making bold proclamations about how they’re going to “solve” cancer or coming up with new “theories” to explain cancer. That’s not to say that cancer research can’t benefit from new perspectives from different sciences and disciplines can bring or new ways of thinking about the problem of cancer. I might seem …
Sayer Ji: Outraged that Google views “vaccine safety questions” to be akin to Pizzagate
Sayer Ji is outraged by a "Google Document Dump" that allegedly shows that Google views antivaccine views as being similar to conspiracy theories like Pizzagate, QAnon, Holocaust denial, and the like. I'm surprised that, if these documents are real, Google actually "gets" what antivaccine views are.
Can the Cancer Moonshot do what its advocates promise?
The Cancer Moonshot. It’s a topic that I’ve been meaning to address ever since President Barack Obama announced it in his State of the Union address this year and tasked Vice President Joe Biden to head up the initiative. Biden, you’ll recall, lost his son to a brain tumor . Yet here it is, eight months later, and somehow I still haven’t gotten around to it. The goal of the initiative is to “eliminate cancer as we know it,” and to that end, with $195 million invested immediately in new cancer activities at the National Institutes of Health and $755 …
Yet another woman with breast cancer lured into quackery by Ty Bollinger and “holistic” medicine advocates
To say that I, as a cancer surgeon, am not a fan of Ty Bollinger is a massive understatement. He’s not exactly one of my fans, either, but I view the hatred of a man like Bollinger directed at me as a badge of honor. Indeed, if a man like Bollinger didn’t detest me, I would view my efforts as a failure because I view him as a quack whose desperately deceptive film series The Truth About Cancer has been correctly dubbed untruthful about cancer by Harriet Hall and whose message has led cancer patients into rejecting conventional medicine in …
Evidence-based medicine guidelines versus patient wishes
There’s a misconception that I frequently hear about evidence-based medicine (EBM), which can equally apply to science-based medicine (SBM). Actually, there are several, but they are related. These misconceptions include the idea that EBM/SBM guidelines are a straightjacket, that they are “cookbook medicine,” and that EBM/SBM should be the be-all and end-all of how to practice clinical medicine. New readers might not be familiar with the difference between EBM and SBM, and here is not the place to explain the difference in detail because this post isn’t primarily about that difference. The CliffsNote version is that EBM fetishizes the randomized …
Autism prevalence increases, and antivaxers blame it on vaccines (2018 edition)
As it does every two years, the CDC has issued its 2018 report on autism prevalence. As in years past, autism prevalence has ticked upward. As in years past, antivaxers have tried to blame it on vaccines. As in years past, they're wrong. Vaccines are not responsible for increased autism prevalence.
Functional medicine (FM) quackery dissected in the mainstream media
Functional medicine (FM) is "make it up as you go along" quackery that combines the "worst of both worlds," namely the overtesting and overtreatment that can plague conventional medicine plus the quackery "integrated" into "integrative medicine." It's rare to see a mainstream outlet get it right about FM, but an Irish journalist pulls it off.
John Horgan is “skeptical of skeptics,” or: Homeopathy and bigfoot versus cancer and the quest for world peace
Contrary to what some of my detractors think, I don’t mind criticism of my viewpoints. After all, if I never encounter criticism, how will I ever improve? On the other hand, there are forms of criticism that are what I would call less than constructive. One form this sort of criticism takes is obsessive repetition of points that have already been addressed and failure to pay attention to how they were addressed. This is the sort of criticism that will eventually provoke an exasperated shrug of the shoulders or even an angry—dare I say Insolent?—retort. Another way criticism can get …
“Liquid biopsies” for cancer: not ready for prime time
I’ve written many times about how the relationship between the early detection of cancer and decreased mortality from cancer is not nearly as straightforward as the average person—even the average doctor—thinks, the first time being in the very first year of this blog’s existence. Since then, the complexities and overpromising of various screening modalities designed to detect disease at an early, asymptomatic phase have become a relatively frequent topic on this blog. Even more than ten years ago, I noted that screening MRI for breast cancer and whole body CT scans intended to detect other cancers early were not scientifically …
