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Antivaccine nonsense Medicine Politics

Transmission gambit: An old antivax trope is resurrected

Recently, antivaxxers were all over social media after Tucker Carlson touted a “revelation” that the phase 3 clinical trial used to support licensure of the Pfizer COVID-19 vaccine didn’t examine its ability to block transmission as meaning that its inability to block transmission had been “covered up”. It wasn’t, and antivaxxers are ignoring everything we’ve learned over the last two years to make the claim that vaccines “don’t prevent transmission”.

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Clinical trials Medicine Personal Politics Popular culture Skepticism/critical thinking

Henry Ford Hospital hydroxychloroquine trial: Not good evidence that the drug works for COVID-19

Recently, Henry Ford Hospital published a study of hydroxychloroquine for COVID-19 that showed a benefit. Unfortunately, it was a bias-prone retrospective study. That didn’t stop President Trump from touting the drug again.

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Cancer Clinical trials Medicine Quackery

Acupuncture for xerostomia: Spin, spin, spin a negative study!

Investigators at M.D. Anderson Cancer Center reported the results of a trial of acupuncture for xerostomia (dry mouth) secondary to radiation therapy for head and neck cancers. It was a negative trial, but investigators still tried to spin it as positive, but with a twist. There was a large difference between results found at M.D. Anderson and the second site in China. What could be going on?

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Bad science Bioethics Clinical trials

Pay-to-play clinical trials: The HHS Secretary’s Advisory Committee on Human Research Protections (SACHRP) weighs in

The ethics of pay-to-play clinical trials are a minefield. Last week the HHS Secretary’s Advisory Committee on Human Research Protections (SACHRP) stepped into that minefield. Are “pay-to-play” clinical trials ever ethically acceptable?

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Clinical trials Complementary and alternative medicine Integrative medicine Medicine Skepticism/critical thinking

A bait-and-switch study of acupuncture in stable chronic angina

This week, JAMA Internal Medicine published a clinical trial purporting to find that acupuncture helps stable angina. Here’s a hint: It doesn’t. It’s a bait-and-switch study that used “electroacupuncture” instead of acupuncture with poor blinding and lack of consideration of prior plausibility.