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Clinical trials Medicine Science

About that Danish mask study that “shows that masks don’t work”…

Danish researchers published a negative randomized controlled study of masks to prevent COVID-19. Is this slam dunk evidence that masks don’t work? Not so fast, there pardner…

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Autism Complementary and alternative medicine Medicine Politics Pseudoscience Quackery Skepticism/critical thinking

The new Secretary of Health and Human Services is a member of a fringe medical organization. Here’s what that means.

I’m always hesitant to write about matters that are more political than scientific or medical, although sometimes the sorts of topics that I blog about inevitably require it (e.g., the 21st Century Cures Act, an act that buys into the myth that to bring “cures” to patients faster we have to neuter the FDA and […]

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Bioethics Cancer Clinical trials Medicine Science Skepticism/critical thinking

Evidence-based medicine guidelines versus patient wishes

There’s a misconception that I frequently hear about evidence-based medicine (EBM), which can equally apply to science-based medicine (SBM). Actually, there are several, but they are related. These misconceptions include the idea that EBM/SBM guidelines are a straightjacket, that they are “cookbook medicine,” and that EBM/SBM should be the be-all and end-all of how to […]

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Clinical trials Complementary and alternative medicine Medicine Popular culture Science Skepticism/critical thinking

Better late than never: Orac comments on the hijacking of evidence-based medicine

It’s no secret that I’m a fan of John Ioannidis. (If you don’t believe me, just type Ioannidis’ name into the blog search box and see how many posts you find.) Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, […]

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Antivaccine nonsense Autism Complementary and alternative medicine Medicine Skepticism/critical thinking

Contrary to antivaccine claims, childhood immunization schedules are evidence-based

I write about vaccines a lot here at Respectful Insolence, and for a very good reason. Of all the medical interventions devised by the brains of humans, arguably vaccines have saved more lives and prevented more disability than any other medical treatment. When it comes to infectious disease, vaccination is the ultimate in preventive medicine, […]