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Clinical trials Medicine Politics Popular culture Skepticism/critical thinking

WTF happened to John Ioannidis?

John Ioannidis is one of the most published and influential scientists in the world, someone whose skewering of bad medical research we at SBM have frequently lauded over the years. Then the COVID-19 pandemic hit. Since then, Prof. Ioannidis has been publishing dubious studies that minimize the dangers of the coronavirus, shown up in the media to decry “lockdowns,” and, most recently, “punched down”, attacking a graduate student for having criticized him. What happened? Did Prof. Ioannidis change, or was he always like this and I just didn’t see it? Either way, he’s a cautionary tale of how even science watchdogs can fall prey to hubris.

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Antivaccine nonsense Bad science Medicine Pseudoscience Skepticism/critical thinking

Poor, poor, pitiful Prof. Gøtzsche: Antivaxxers and COVID-19 cranks are quoting him in support of their pseudoscience

Prof. Peter Gøtzsche really, really doesn’t like that COVID-19 deniers and antivaxxers are quoting him to support their misinformation. He has no one to blame but himself. He is a useful idiot for such people.

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Biology Cancer Clinical trials Medicine Pseudoscience Skepticism/critical thinking

Is there a reproducibility "crisis" in biomedical research?

Most scientists I know get a chuckle out of the Journal of Irreproducible Results (JIR), a humor journal that often parodies scientific papers. Back in the day, we used to chuckle at articles like “Any Eye for an Eye for an Arm and a Leg: Applied Dysfunctional Measurement” and “A Double Blind Efficacy Trial of […]

Categories
Clinical trials Complementary and alternative medicine Medicine Popular culture Science Skepticism/critical thinking

Better late than never: Orac comments on the hijacking of evidence-based medicine

It’s no secret that I’m a fan of John Ioannidis. (If you don’t believe me, just type Ioannidis’ name into the blog search box and see how many posts you find.) Over the last couple of decades, Ioannidis has arguably done more to reveal the shortcomings of the medical research enterprise that undergirds our treatments, […]

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Complementary and alternative medicine Medicine Science Skepticism/critical thinking

Science isn’t perfect, but it’s better than the alternative.

It often comes as a surprise to proponents of alternative medicine and critics of big pharma that I’m a big fan of John Ioannidis. Evidence of this can easily be found right here on this very blog just by entering Ioannidis’ name into the search box. Indeed, my first post about an Ioannidis paper is […]