Categories
Antivaccine nonsense Clinical trials

“No saline placebo-controlled vaccine trials”: An old antivax trope

Robert F. Kennedy, Jr. has resurrected the antivax claim that the childhood vaccine schedule has never been tested in randomized controlled trials (RCTs) with a saline placebo controls (and therefore the vaccine schedule is unsafe). This is an old and deceptive antivax half-truth that ignores both what constitutes a scientifically valid placebo and the ethical requirements for RCTs.

Categories
Antivaccine nonsense Medicine Politics Popular culture

Return of the revenge of “no saline placebo RCTs” for childhood vaccines

Thanks to RFK Jr. the deceptive claim that the childhood vaccine schedule has never been tested in a randomized controlled trial with a saline placebo control is making the rounds again.This is an old and deceptive antivax half-truth that ignores both what constitutes a scientifically valid placebo and the ethical requirement that RCTs have clinical equipoise.

Categories
Clinical trials Medicine Skepticism/critical thinking

The Cochrane mask fiasco: Does EBM predispose to COVID contrarianism?

Earlier this month the Cochrane Collaborative was forced to walk back the conclusions of a review by Tom Jefferson et al that had been spun in the media as proving that “masks don’t work.” Tom Jefferson himself has been problematic about vaccines for a long time, but the rot goes deeper. What is it about the evidence-based medicine paradigm that results in misleading conclusions?

Categories
Antivaccine nonsense Bad science Clinical trials Medicine

Peter Doshi vs. COVID-19 vaccines, the latest round

BMJ Senior Editor Peter Doshi published a preprint misleadingly “reanalyzing” phase 3 clinical trials to falsely conclude that mRNA vaccines to cause more harm than good. I sense…p-hacking. That, and comparing apples to oranges.

Categories
Clinical trials Homeopathy Medicine Quackery

Why are so many clinical trials of homeopathy “positive”?

Homeopathy is The One Quackery To Rule Them All. Why, then, can homeopaths seemingly cite so many “positive” randomized clinical trials to support it?